Thursday 9 August 2007

Cilia - Unexpected

"For a long time, cilia were regarded as lowly janitors, lining our airways and beating in coordination to sweep up dirt and mucus, or wafting eggs down fallopian tubes. True, they had shown flashes of brilliance: single cilia, called kinocilia on the hair cells in the inner ear, for example, help us to hear. Cilia play similar roles in sight and smell, but biologists have only recently started to realize that cells carrying cilia are far from exceptions. Almost every cell in the human body carries a cilium, even neurons buried deep in the brain."
- (Kindly see full article here: http://www.nature.com/nature/journal/v448/n7154/full/448638a.html )
This is also a new interesting addition: A highly selective fluorescent probe for in vivo monitoring of mercury (Nature)
And, This must be very interesting and useful for determining where proteins bind to DNA on a genome-wide scale is important for understanding how gene expression is regulated: DamID: a tool for studying genome-wide protein:DNA interactions.

It uses a targeted methylation approach to map protein binding sites. It is an attractive alternative to chromatin immunoprecipitation (ChIP)-based methods, particularly when high quality antibodies are not available.

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